© Toulis KA, Robbins T, Reddy N, et al.

Temozolomide: a novel treatment for pituitary carcinoma. Tirosh A, Shimon I. These include prolactin-releasing factors (PRFs) and prolactin-inhibitory factors (PIFs).Dopamine (DA) is the principal PIF, and thyrotropin-releasing hormone (TRH), vasoactive intestinal peptide, and peptide histidine methionine are the putative PRFs. A prolactinoma is a benign (noncancerous) tumor of the pituitary gland that produces a hormone called prolactin. Melasma (Chloasma) — Definition and Treatment Please confirm that you would like to log out of Medscape.

A comparison of cabergoline and bromocriptine in the treatment of hyperprolactinemic amenorrhea. Raverot G, Burman P, McCormack AI, et al. Management of prolactinoma with cabergoline treatment in a pregnant woman during her entire pregnancy. Progress in the management of hyperprolactinemia. Kallmann Syndrome and Idiopathic Hypogonadotropic HypogonadismA New Oral Testosterone Undecanoate Formulation Restores Testosterone to Normal Concentrations in Hypogonadal MenNew Oral Testosterone Undecanoate Formulation Restores Normal Testosterone Levels£700,000 Klinefelter's Settlement: Why Honesty Matters in Medicine Growth Disorders: 10 Cases of a Developing ProblemLate Dinner Affects Metabolism, May Lead to Weight Gain, DiabetesMetabolic Disease: Is It the Fat, Sugar, or Processed Food? Surgery as a Viable Alternative First-Line Treatment for Prolactinoma Patients. This website also contains material copyrighted by 3rd parties. (2011). It is only used when there is a For patients with resistant prolactinomas and persistent hyperprolactinemia despite medical treatment, surgical debulking with or without radiation therapy and temozolomide (for malignant prolactinoma) are indicated. Whitelaw BC, Dworakowska D, Thomas NW, et al. Located at the base of the brain, the pituitary is a pea-sized gland that controls the production of many hormones. (2007). Prolactinoma-associated headache and dopamine agonist treatment. Transcranial resection of a pituitary tumor is indicated only in patients with significant extrasellar extension.Radiation is rarely used as a primary treatment to manage prolactinoma. Disease-specific impairments in quality of life during long-term follow-up of patients with different pituitary adenomas. Physiological Reviews, 80(4), 1523-1631.Imran, S. A., Ur, E., & Clarke, D. B. Prolactinoma — Diagnosis and Treatment

Frieze TW, Mong DP, Koops MK.

Schlechte J, Dolan K, Sherman B, et al. Serum prolactin levels in untreated primary hypothyroidism. The physiologic role of these PRFs is not established. Chahal HS, Stals K, Unterländer M, Balding DJ, Thomas MG, Kumar AV, et al. Colao A, Di Sarno A, Sarnacchiaro F, et al. Carter JN, Tyson JE, Tolis G, et al. Macroprolactinomas: retrospective follow up study in the MR imaging and correlation with clinical symptomatology. Lim S, Shahinian H, Maya MM, Yong W, Heaney AP. Temozolomide in the management of dopamine agonist-resistant prolactinomas. Drugs Zhang F, Chen J, Lu Y, et al. /viewarticle/934339 Elevated prolactin level has a direct effect on bone and leads to increased bone turnover in both genders.Symptoms mainly occur in individuals with macroprolactinoma. Current approach to treatments for prolactinomas. A. These tumors rarely occur in children.The etiology of prolactinomas is obscure. Strict editorial standards and an effective quality management system help us to ensure the validity Kars M, Roelfsema F, Romijn JA, Pereira AM. 2020 Lecturio GmbH. Symptoms and complications arising from space-occupying lesions of prolactinomas are Macroprolactinoma can also compress the surrounding normally functioning pituitary tissue, resulting in a deficiency of TSH, GH, or ACTH.Women intolerant to oral bromocriptine may be prescribed intravaginal bromocriptine as it is equally effective.The adverse reactions of bromocriptine include dizziness, nausea, nasal congestion, and orthostatic hypotension.Patients unresponsive or intolerant to bromocriptine may be prescribed cabergoline at a twice-weekly dose owing to its long half-life. US National Guidelines Clearinghouse. PGRpdiBpZD0idmlkZW8tcG9wdXAtMSIgc3R5bGU9IndpZHRoOiAxMDAlOyBoZWlnaHQ6IDEwMCU7Ij48aWZyYW1lIHdpZHRoPSIxMDAlIiBoZWlnaHQ9IjEwMCUiIHNyYz0iaHR0cHM6Ly93d3cueW91dHViZS5jb20vZW1iZWQvdzZQMFVrVDlZSzA/cmVsPTAmY29udHJvbHM9MCZzaG93aW5mbz0wIiBmcmFtZWJvcmRlcj0iMCIgYWxsb3dmdWxsc2NyZWVuPjwvaWZyYW1lPjwvZGl2Pg==Sign up to get access to 250+ video lectures for free! Swords F, Monson J, Besser GM, et al. Long-Term Follow-Up of Primary Medical Versus Surgical Treatment of Prolactinomas in Men: Effects on Hyperprolactinemia, Hypogonadism, and Bone Health.


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